Twikirize Bright2024-09-192024-09-192023http://hdl.handle.net/20.500.12284/715Introduction: In an effort to reduce cervical cancer burden, many governments have emphasized Human Papilloma Virus (HPV) vaccine as an important prevention strategy. Despite its effectiveness in preventing human papilloma virus (HPV) infection and free HPV immunization programs, vaccine acceptance is not guaranteed as some cultures are still against it due to various reasons. This study was conducted to assess the knowledge, attitude and perception of human papilloma Virus vaccination (HPV) among parents of young girls (aged 8 – 12) in Mbarara City. Methodology: The study was cross sectional in nature employing both qualitative and quantitative approaches for data collection and analysis. Information was collected from a sample of 288 respondents and 12 key informants using questionnaire and interviews. Data was analyzed using Microsoft Excel and STATA Version 18.0 Results: The study discovered that level of Knowledge on HPV vaccination among parents of young girls was relatively low (41.3%) despite most respondents revealing to have heard about HPV and its associated infections like cervical cancer and genital warts. The study also found out that a large portion of community members (62.1%) still had negative attitudes towards the vaccine which has negatively affected their perceptions. Negative attitudes and perceptions equally played a big role towards vaccination leading to low vaccine acceptability in the area. The study further discovered a wide knowledge gap about HPV infection and HPV vaccine uptake (42%) and this has to be addressed. Conclusion: In conclusion, the study confirmed that knowledge about human papilloma virus vaccination (HPV) was low and attitude and perception of human papilloma virus vaccination (HPV) was poor among parents of young girls (aged 8 – 12). Recommendations: Engaging all key stakeholders through improved and increased education will elevate public trust. There is need to engage health care providers who include Doctors, nurses and public Health specialists in community sensitization on the benefits of the vaccination Tailored community-based interventions and sensitization programs are a viable means to achieve this for multiple reasons.en-USAttribution-NonCommercial-NoDerivs 3.0 United Stateshttp://creativecommons.org/licenses/by-nc-nd/3.0/us/Thesis